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Wednesday, September 8, 2021

Cell Organelles

Biology Index

Where are we going with this? The information on this page should increase understanding related to this standard:  Evaluate comparative models of various cell type…Evaluate eukaryotic and prokaryotic cells.


Article includes ideas, images, and content from Troy Smigielski (2021-09)

Cell Organelles

(Do they play music??)

https://www.google.com/search?q=cell+organelles

Okay… starting with cell theory, we are expected to agree that…

Wait, we did that already! Okay, what next?

Let's look at those organelles we find inside the cells!

How about we start with a definition?

"An organelle (think of it as a cell’s internal organ) is a membrane bound structure found within a cell. 

Just like cells have membranes to hold everything in, these mini-organs are also bound in a double layer of phospholipids to insulate their little compartments within the larger cells. You can think of organelles as smaller rooms within the factory, with specialized conditions to help these rooms carry out their specific task (like a break room stocked with goodies or a research room with cool gadgets and a special air filter). These organelles are found in the cytoplasm, a viscous liquid found within the cell membrane that houses the organelles and is the location of most of the action happening in a cell." 



Nucleus

The nucleus houses the cell’s DNA in chromosomes (chromatin) and controls cell activities. The nucleus protects the DNA. If the DNA was not kept safe inside the nucleus, it would be vulnerable to damage from other things.

Not all cells have a nucleus. For instance, red blood cells do not. The function of red blood cells is to carry oxygen throughout the organism. Without a nucleus, they can carry ore oxygen.

So, does this make red blood cells prokaryotic? Not actually. They start out as eukaryotic cells, but as they develop, the get rid of their nucleus.

Source, 2021-09

Consider this: Some breeds of dogs have their tails cropped-off routinely. Removing a part of the tail does not cause them to stop being dogs. In the same way, "cropping off" the nucleus does not cause a red blood cell to stop being eukaryotic.


 
But back to that genetic information in the nucleus… In the nucleus, the genetic information (DNA double helix) is packaged by special proteins (histones) to form a complex called chromatin. The chromatin undergoes further condensation to form the chromosome. (Source, 2021-09)

https://www.google.com/search?q=chromatin


So, to sum it up a little, the nucleus houses the genetic information in chromosomes.

The nuclear components are suspended within the nucleus in a gel-like substance called nucleoplasm.

Nucleolus

The nucleolus is located inside the nucleus of a cell. The nucleolus is not bound by a membrane, so it actually isn't an organelle, but it is notable enough to warrant discussion. 

The nucleolus is a space that forms near the DNA and there, it makes ribosomal subunits. Ribosomes are assembled in the nucleolus and exit the nucleus through openings called nuclear pores.




Ribosomes

Ribosome parts are built in the nucleolus. Both prokaryotic cells and eukaryotic cells have ribosomes. 

The function of ribosomes is to build proteins.  




Rough Endoplasmic Reticulum

Rough endoplasmic reticulum helps fold and modify proteins. It is studded with ribosomes. 

This is the assembly line of the cell that has ribosomes as the workers.




Smooth Endoplasmic Reticulum

Smooth endoplasmic reticulum makes lipids, steroid hormones, and it helps in the detoxification of byproducts. It does not have ribosomes.




Golgi Apparatus (AKA Golgi Body)

Packages and ships proteins once they are made.

A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and lipid molecules, especially proteins destined to be exported from the cell.

https://www.google.com/search?q=golgi+apparatus



Lysosome and Peroxisome

Have digestive enzymes that break down waste, food particles, and/or bacteria or viruses.


Mitochondrion (POWERHOUSE OF THE CELL)

The mitochondrion has the function in the cell to make ATP (adenosine 5'-triphosphate, cellular energy).  More on that can be found HERE.

The mitochondrion is the site of cellular respiration.


Vesicles

Molecules used for transport. 

These are the "boxes" that proteins get packed into.


Plasma Membrane

Both prokaryotic cells and eukaryotic cells have a plasma membrane. It is also called a cell membrane or cytoplasmic membrane. 

Controls what enters and exits the cell.

The plasma membrane is made up of a phospholipid bilayer.



Cytoplasm

Surrounding all of the organelles within the cell is a fluid-like material called cytoplasm. 



Putting it all together…

Well, cells vary in composition based on their function within the organism, but, a good, general picture of a cell includes ten key organelles, plus the cytoplasm in which they all are arranged.

Working together, all of the organelles carry out the work needing to be performed by the cell.




The Cell in Action

Thinking about how the cells carry out their work, it is convenient to think of some organelles as systems working closely together. One set of organelles forms what is called the endomembrane system.

The endomembrane system consists of the endoplasmic reticulum, the Golgi apparatus, and the vesicles. 

These three organelles work together to make, package, and transport proteins. 



Plant Cells

Plant cells have a few additional organelles. These organelles have important functions in plants, and are not found in animals.


Vacuole

"A vacuole is a membrane-bound cell organelle. In animal cells, vacuoles are generally small and help sequester waste products. In plant cells, vacuoles help maintain water balance. Sometimes a single vacuole can take up most of the interior space of the plant cell." (Source, 2021-09)

Plant cells have an organelle for storage. The large central, vacuole functions to store materials like water, sugar, or waste.

Some animal cells also have vacuoles.  However, in animals, vacuoles are smaller than their plant counterparts. However, in animals, vacuoles also usually appear in greater numbers. (Source, 2021-09) There are also animal cells that do not have any vacuoles. (Source, 2021-09)



Chloroplast

The chloroplast is the site of photosynthesis, which makes sugar for the plant.

275 ' Tall Tree

Cell Wall

The cell wall of plant cells functions to give structure and rigidity to cell. It also provides protection. It is made of cellulose (a carbohydrate, a polysaccharide).

The cell wall’s rigidity allows trees to grow up to 400 feet tall without falling over.







Mitochondrion vs. Chloroplast

The mitochondrion is site of cellular respiration and creates energy in the form of ATP.  The chloroplast is the site of photosynthesis and creates energy in the form of glucose (or other sugars).

Both animal and plant cells have mitochondria.




Both animal and plant cells need ATP.

However, only plants have chloroplasts. Animals do not carry out photosynthesis; the chloroplasts function as the location whereby photosynthesis takes place in plants.




How about a chart? That would be cool!


Cell Organelles and their Functions

Function

Organelle

• houses the cell’s DNA in

chromosomes (chromatin).


• controls cell activities

Nucleus

• makes ribosomal subunits

Nucleolus

• build proteins

Ribosomes

• allows ribosomal subunits to exit the nucleus


Nuclear Pores

• helps fold and modify proteins.

• studded with ribosomes

Rough Endoplasmic Reticulum

• makes lipids, steroids and 

hormones.


• helps in the detoxification of byproducts.

• does not have ribosomes.

Smooth Endoplasmic Reticulum



• packages and ships proteins once they are made.

Golgi Apparatus

• have digestive enzymes that break down waste, food particles, and/or bacteria or viruses.

Lysosome and Peroxisome

• makes ATP

• site of cellular respiration

Mitochondrion

• molecules used for transport. 

Vesicles

• controls what enters and exits the cell.


• made up of a phospholipid bilayer.


Plasma Membrane

• a fluid-like material that surrounds all of the organelles within the cell. 

Cytoplasm

• the site of photosynthesis, which makes sugar 

Chloroplast (plants only)

• gives structure and rigidity to cell

Cell Wall (plants only)

• store materials like water, sugar, or waste.

Vacuole (plants mostly)



 

Tuesday, September 7, 2021

Eukaryotic and Prokaryotic Cells

Biology Index

Where are we going with this? The information on this page should increase understanding related to this standard:  Evaluate comparative models of various cell type…Evaluate eukaryotic and prokaryotic cells.


Article includes ideas, images, and content from Troy Smigielski (2021-09)

Eukaryotic and Prokaryotic Cells
(Hmm… What now?)

Okay… starting with cell theory, we are expected to agree that:
  1. All living organisms are made up of cells.
  2. Cells are the basic unit of life.
  3. All cells come from pre-existing cell.

Furthermore, all cells are made up from four basic biomolecules. 

But all cells are not the same. There are two basic types of cells: eukaryotic and prokaryotic.


Eukaryotic Cells

The first type of cell we will discuss are called eukaryotic cells. To begin with, eukaryotic cells have a nucleus and membrane-bound organelles.



So, just what are membrane-bound organelles?

A membrane is an outer lining or covering. 

Organelles are the smaller parts of the cell that have specific functions.

For example, the nucleus or the mitochondria are membrane-bound organelles. The organelles are the parts that make up a cell. 

Secondly, eukaryotic cells have ribosomes, which are organelles that make proteins.


Additionally, eukaryotic cells are larger and more complex than prokaryotic cells. Prokaryotic cells  are between 1 µm and 10 µm while eukaryotic cells are between 10 µm and 100 µm in size.

It is worth nothing here that plant cells have a cell wall whereas animal cells do not. So, eukaryotic cells occur both with and without cell walls.

Based on having eukaryotic cells, some organisms are classified as eukaryotes.

Source: Google

If an organism has eukaryotic cells, it is said to be a eukaryote. Alternately, if an organism has prokaryotic cells, it is said to be a prokaryote.

Okay, cool…

Eukaryotes are generally multicellular although they can be unicellular. For instance, diatoms are unicellular eukaryotes that produce ~20% of earth’s oxygen.

Examples of eukaryotes include animals, plants, and fungi.

By File:Osmia rufa couple (aka).jpg: André KarwathFile:Boletus edulis (Tillegem).jpg: Hans HillewaertFile:Volvocales.png: Aurora M. NedelcuFile:Lightmatter chimp.jpg: Aaron LoganFile:Ranunculus asiaticus4LEST.jpg: Leif StridvallFile:Isotricha intestinalis.jpg: Agricultural Research ServiceCompilation: Vojtěch Dostál - File:Osmia rufa couple (aka).jpgFile:Boletus edulis (Tillegem).jpgFile:Volvocales.pngFile:Lightmatter chimp.jpgFile:Ranunculus asiaticus4LEST.jpgFile:Isotricha intestinalis.jpg, CC BY-SA 2.5, https://commons.wikimedia.org/w/index.php?curid=5321214



Some eukaryotic cells will have flagella and/or cilia. These function in cellular movement. The singular of flagella is flagellum.

In eukaryotes, DNA is housed in the nucleus in structures called chromosomes (chromatin).

Eukaryotic Cells Summary:
  • Eukaryotic cells have a nucleus and membrane-bound organelles.
  • Eukaryotic cells have ribosomes, which are organelles that make proteins.
  • Eukaryotic cells are larger and more complex than prokaryotic cells. 
  • Based on having eukaryotic cells, some organisms are classified as eukaryotes.
  • DNA is housed in the nucleus in structures called chromosomes (chromatin).

Prokaryotic Cells

The next type of cell we will discuss are called prokaryotic cells. Prokaryotic cells do NOT have a nucleus and do NOT have membrane-bound organelles.

All prokaryotes have a cell wall.

Prokaryotic cells also have ribosomes.

Prokaryotic cells are smaller and less complex than eukaryotes.

Organisms made up of prokaryotic cells are called prokaryotes.

Prokaryotes are usually unicellular although there is some debate that they can be multicellular.

Examples of prokaryotes are bacteria and archaea.


Prokaryotes
https://www.google.com/search?q=prokaryotes


Another difference between eukaryotes and prokaryotes is found in the way they arrange their DNA. Recall that in eukaryotes, DNA is housed in the nucleus in structures called chromosomes (chromatin). In prokaryotes, DNA is floating freely in one chromosome and is circular in shape.

There are extra pieces of DNA called plasmids that can be transferred to other prokaryotes. These typically carry favorable genes like antibiotic resistance.


Prokaryotic Cells Summary:
  • All prokaryotes have a cell wall.
  • Prokaryotic cells also have ribosomes.
  • Prokaryotic cells are smaller and less complex than eukaryotes.
  • Organisms made up of prokaryotic cells are called prokaryotes.
  • Prokaryotes are usually unicellular, although there is some debate that they can be multicellular.
  • DNA is floating freely in one chromosome and is circular in shape.


__________________________


The Endosymbiotic Theory

Source
If all cells come from other cells… where did the original cells come from? In an attempt to explain a process that would explain the presence of the existing variances in cells, biologists have constructed a theory.

"The endosymbiotic theory states that some of the organelles in today's eukaryotic cells were once prokaryotic microbes. In this theory, the first eukaryotic cell was probably an amoeba-like cell that got nutrients by phagocytosis and contained a nucleus that formed when a piece of the cytoplasmic membrane pinched off around the chromosomes. Some of these amoeba-like organisms ingested prokaryotic cells that then survived within the organism and developed a symbiotic relationship. Mitochondria formed when bacteria capable of aerobic respiration were ingested; chloroplasts formed when photosynthetic bacteria were ingested. They eventually lost their cell wall and much of their DNA because they were not of benefit within the host cell. Mitochondria and chloroplasts cannot grow outside their host cell." (Source, 2021-09-07)  

According to the endosymbiotic theory one ancestral prokaryote (with no membrane bound organelles) ingested a mitochondrion. 

Rather than the mitochondrion being broken down, the two cells began to live in symbiosis which is where they help each other out. 


https://ib.bioninja.com.au/standard-level/topic-1-cell-biology/15-the-origin-of-cells/endosymbiosis.html



This process continued until the modern-day eukaryote evolved with many organelles. 

So, according to the theory, the complex arrangement of the eukaryotic cells resulted from the happenstance merger of smaller prokaryotic cells that resulted in a symbiotic relationship. The repeated occurrence of these mergers eventually produced the various, specific-functioning cells we can identify now.



__________________________

Wow! That's a lot of stuff about something so small! Seriously… How about a chart?


Comparison of Eukaryotic and Prokaryotic Cells



Prokaryotic

Eukaryotic

Nucleus?

No

Yes

Membrane-bound organelles?

No

Yes

Cell wall?

Yes

Animal - No

Plant - Yes

General Cell Type

Unicellular

Multicellular

Cell size

Smaller

Larger, more complex

DNA Location

Floating freely

Within nucleus

Examples

Bacteria

Animals

Plants.




Thursday, September 2, 2021

Nucleic Acids

Biology Index

Where are we going with this? The information on this page should increase understanding related to this standard:  Evaluate comparative models of various cell types with a focus on organic molecules that make up cellular structures.

Article includes ideas, images, and content from Troy Smigielski (2021-09)

Nucleic Acids
(Hmm… What now?)

So… yet one more biomolecule… Let's get going!

Nucleic acids function to store genetic information and provide instructions for building proteins.


Nucleic acids are made of nucleotides.

That means that the monomer for nucleic acids are nucleotides.


Source


A nucleotide is made up of:

sugar + phosphate + nitrogenous base 

The nitrogen bases in DNA can be broken down into two categories: Purines and Pyrimidines.

Purines have 2 rings. Examples are Adenine (A) and Guanine (G).

Pyrimidines have 1 ring. Examples are Cytosine (C), Thymine (T), and Uracil (U).




Chargaff’s Rules


In nucleic acids…
…a purine will ALWAYS bond with a pyrimidine.
…the A pairs with T or U.
…the C pairs with G.

…the number of A and T is always the same.

…the number of C and G is always the same.



In each nucleotide, you have a sugar, a phosphate, and a nitrogen base.

The nitrogen base will be A, G, C, or T (in DNA).

If the base is A, then there will be a T on the other side of it.

Likewise for C and G














Two Kinds of Nucleic Acids


There are 2 kinds of nucleic acids:
DNA: locked inside the nucleus
RNA: can leave the nucleus


DNA = DeoxyriboNucleic Acid

RNA = RiboNucleic Acid

So… what's the the difference between DNA and RNA?


DNA: stuck in nucleus
  • Double-stranded (double-helix)
  • Main information molecule


RNA: can leave nucleus
  • Single-stranded
  • Functions mainly as a middle man for making proteins




How do nucleic acids apply to real life?

DNA is often used to convict or exonerate suspects from a crime. Most people have seen the TV show, CSI. DNA analysis is a common aspect of that show, just as it is in many major crime investigations.

How does it work? The DNA code is represented by bands that can be compared much like fingerprints are compared, but… You can't hide your DNA by wearing gloves!






Wednesday, September 1, 2021

Acceleration and Displacement

Physics Index

Where are we going with this? The information on this page relates to the skills needed to investigate and evaluate the graphical and mathematical relationship (using either manual graphing or computers) of one-dimensional kinematic parameters (distance, displacement, speed, velocity, acceleration) with respect to an object's position, direction of motion, and time.

Acceleration and Displacement
(Okay, NOW we're moving!)

There it is… at rest.

Then, it begins to move! Bam! Now, it's somewhere else! Where? Where is it?

Let's start with a reference point and an object some distance from it.

An object is 3 meters from a point… (That is to say, an object has an initial distance of 3 meters from a point.)

So, if it doesn't move, then (duh) the final distance from the reference point is the same as the initial distance…

df = di

That's easy…

Now, suppose it moves. And we'll call that motion ∆d… then

df = di  + ∆d

If we understand that ∆d is a function of the rate of motion, velocity, and how long it moves, then

∆d = vave • t

So, we can substitute…

df = di  + vave • t

Okay, so far so good. Now, if an object is accelerating, then the velocity is changing. We can find the average velocity as…

vave = (vf + vi)/2

where is vf  final velocity and vi is initial velocity.

But wait! There's more!

The final velocity can be found! Where vf  is final velocity and vi  is initial velocity and ∆v is the change in velocity then

vf = vi + ∆v

and since

∆v = at

then

vf = vi + at


We should plug that into… something…

df = di  + vave • t

df = di  + (vf + vi)/2 • t

df = di  + (( vi + at) + vi)/2 • t

And then, math-magic occurs and…

df = di  + (vi t) + (1/2 at2)          <--- Parenthesis added for clarity

The above equation will become the starting point for many motion problems. It is worth committing to memory or recording in a convenient place for reference.

Generally, it will be written without the parenthesis as…

df = di  + vi t + 1/2 at2

 



______________________


Seriously! How about doing that again with colors?

 df = di  + ∆d

 

∆d = vave • t

vave = (vf + vi)/2

 

vf = vi + ∆v

∆v = at

vf = vi + at

 
df = di  + ∆d

df = di  + vave • t

df = di  + (vf + vi)/2 • t

df = di  + (( vi + at) + vi)/2 • t


And then, math-magic occurs and…

df = di  + (vi t) + (1/2 at2)          <--- Parenthesis added for clarity

____________________________

Math magic, anyone?


Physics of Motion: Deriving the Distance Equation



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Bill Snodgrass is a life-long teacher/mentor type who likes to see people develop into their best possible selves.